Biology Jobs .com Life Science career site  

Southern Research

Postdoctoral Research Associate in Cancer Research – Dr. Janet Houghton’s Laboratory

Post Date:Mar 20, 2017Type:Full-Time
Start Date:3/20/2017Salary:
Location:US-AL-Birmingham Job Reference:3116

Job Description:
Postdoctoral Research Associate
Cancer Research – Dr. Janet Houghton’s Laboratory
Department of Oncology, Division of Drug Discovery, Southern Research, Birmingham, AL
Postdoctoral Research Associate position available immediately in drug discovery and mechanism-based cancer research in the Department of Oncology, Division of Drug Discovery, at Southern Research.  Research involves small molecule targeting of constitutively expressed oncogenes, and/or key downstream targets or regulators of their aberrant proliferative phenotype, together with detailed mechanistic studies based in cancer drug discovery.  We have identified key genes that regulate cell death in the HH-GLI and KRAS-GLI signaling axes, in the regulation of GLI-dependent transcription and in DNA replication licensing. Colon cancer is the model currently under investigation, with opportunities to extrapolate to other cancer types based on the malignant phenotype, oncogenic KRAS and constitutively activated GLI.  Mechanism-based research areas important for this position include detailed understanding and technical experience in mechanisms of DNA replication licensing, DNA damage and repair, transcriptional regulation, cell death, and/or drug discovery in the cancer field.  Expertise in molecular and cell biology, biochemistry and human cell culture techniques is required. 
In addition to cancer biologists, Southern Research offers a dynamic and collaborative research environment with basic scientists in the fields of small molecule design, computational biology, synthetic chemistry, X-ray crystallography, and high-throughput screening, all contributory to the cancer drug discovery initiative.  Areas in cancer biology are focused in molecular oncology, immuno-oncology, and specific cancer types, while the Division of Drug Discovery offers unique opportunities for career development.  Southern Research Faculty have academic affiliations with the University of Alabama, Birmingham, with full access to seminars, Core Facilities, and activities within the Comprehensive Cancer Center.
Successful candidates should possess the PhD degree in molecular biology, cell biology or relevant scientific discipline with experience in cancer related research, and be committed to the development of a dynamic, academic career in science.  PhD candidates obtaining their diploma in 2017 may be considered, however, the PhD must be awarded before employment can commence. Interested candidates should submit a CV, description of research interests, technical skills, past projects and publications, and contact information for three references.  Candidates should apply directly at, which also provides additional information on this program, and on the six Departments that comprise the Division of Drug Discovery.

Contact Information
Southern Research

Apply for this Job

Please help us spread the word about by telling any organization you know that hires employees with a background in biology that they can advertise their open positions online at for only $1 per day with unlimited job postings and resume database access plus their organization's profile and logo featured online. You can't beat the affordable advertising rates of Biology Jobs .com combined with the highly tartgeted traffic that your job postings will recieve compared to other online job board services.

Whether you are working on your degree, or your have completed your B.A. (bachelor of arts) B.S. ( bachelor of science ) M.S.( master of science ), M.A. ( master of arts ),or Ph.D ( doctorate of philosophy ) degree , and you are looking for a postdoctoral ( postdoc ) job, Biology Jobs .com has job openings posted online at various times for all levels of Biology Jobs from volunteer positions to postdoctoral research jobs to tenured professors, positions with top biotechnology companies and everything in between.